Product Name: TH287
Chemical Name: 6-(2,3-dichlorophenyl)-N4-methylpyrimidine-2,4-diamine
SMILES Code: NC1=NC(C2=CC=CC(Cl)=C2Cl)=CC(NC)=N1
CAS NO: 217645-70-0 Product: WZ4003
Synonym: TH 287; TH-287
Chemical Formula: C11H10Cl2N4
Appearance: Solid powderWeb Site：Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Neurokinin Receptor inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: TH287 is a potent inhibitor of human 7,8-Dihydro-8-oxoguaninetriphosphatase MTH1 (NUDT1) with an IC50 value of 5 nM and good metabolic stability. Cancers have dysfunctional redox regulation resulting in reactive oxygen species production, damaging both DNPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16173963
