Product Name: Simeprevir
Chemical Name: (2R,3aR,11aS,12aR,14aR,Z)-N-(cyclopropylsulfonyl)-2-((2-(4-isopropylthiazol-2-yl)-7-methoxy-8-methylquinolin-4-yl)oxy)-5-methyl-4,14-dioxo-1,2,3,3a,4,5,6,7,8,9,11a,12,12a,13,14,14a-hexadecahydrocyclopenta[c]cyclopropa[g][1,6]diazacyclotetradecine-12a-carb
SMILES Code: O=C([C@]12NC([C@@](C[C@@H](OC3=CC(C4=NC(C(C)C)=CS4)=NC5=C(C)C(OC)=CC=C35)C6)([H])[C@]6([H])C(N(C)CCCC/C=C[C@]1([H])C2)=O)=O)NS(=O)(C7CC7)=O
CAS NO: 80573-04-2 Product: Moricizine
Synonym: TMC435; TMC435350; TMC-435350
Chemical Formula: C38H47N5O7S2
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).CGRP Receptor inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Simeprevir (TMC 435350) is a potent inhibitor of HCV NS3/4A protease (Ki = 0.36 nM) and viral replication (replicon EC50 = 7.8 nM).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/8385175
