Product Name: Selumetinib
Chemical Name: 6-(4-bromo-2-chloroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide
SMILES Code: CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO
CAS NO: 917111-44-5 Product: Ecteinascidin-Analog-1
Synonym: AZD6244; Array142886; ARRY-142886; AZD-6244
Chemical Formula: C17H15BrClFN4O3
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Glucokinase inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Selumetinib (AZD6244) is an orally bioavailable small molecule with potential antineoplastic activity. Selumetinib inhibits mitogen-activated protein kinase kinases (MEK or MAPK/ERK kinases) 1 and 2, which may prevent the activation of MEK1/2-dependent efPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21593143
