Product Name: Saridegib
Chemical Name: N-((2S,3R,3aS,3’R,4a’R,6S,6a’R,6b’S,7aR,12a’S,12b’S)-3,6,11′,12b’-tetramethyl-2′,3a,3′,4,4′,4a’,5,5′,6,6′,6a’,6b’,7,7a,7′,8′,10′,12′,12
SMILES Code: CC1CC2C(C(C3(O2)CCC4C5CCC6CC(CCC6(C5CC4=C(C3)C)C)NS(=O)(=O)C)C)NC1
CAS NO: 229971-81-7 Product: Decloxizine
Synonym: IPI-926; IPI 926
Chemical Formula: C29H48N2O3S
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).JAK/STAT_Compound_Library inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Saridegib (IPI-926) is an orally bioavailable, cyclopamine-derived (for structure comparison see Fig 1) inhibitor of the Hedgehog (Hh) pathway with potential antineoplastic activity. Specifically, Hedgehog pathway inhibitor IPI-926 binds to and inhibits tPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/11063609
