Product Name: SAR405838
Chemical Name: (2’S,3R,4’S,5’R)-6-chloro-4′-(3-chloro-2-fluorophenyl)-N-((1r,4R)-4-hydroxycyclohexyl)-2′-neopentyl-2-oxospiro[indoline-3,3′-pyrrolidine]-5′-carboxamide
SMILES Code: O=C([C@H](N[C@H]1CC(C)(C)C)[C@H](C2=CC=CC(Cl)=C2F)[C@@]31C(NC4=C3C=CC(Cl)=C4)=O)N[C@H]5CC[C@H](O)CC5
CAS NO: 332012-40-5 Product: Alantolactone
Synonym: MI-773
Chemical Formula: C29H34Cl2FN3O3
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Toll-like Receptor TLR) inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: SAR405838 (MI-773) is an orally available spiro-oxindole HDM2 (human double minute 2) antagonist with potential antineoplastic activity. Upon oral administration, the p53-HDM2 protein-protein interaction inhibitor MI-773 binds to HDM2, preventing the bindPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21497565
