Product Name: S49076
Chemical Name: (Z)-3-((3-((4-(morpholinomethyl)-1H-pyrrol-2-yl)methylene)-2-oxoindolin-5-yl)methyl)thiazolidine-2,4-dione
SMILES Code: O=C(N1CC2=CC3=C(NC(/C3=CC4=CC(CN5CCOCC5)=CN4)=O)C=C2)SCC1=O
CAS NO: 4368-28-9 Product: CCG-1423
Synonym: S-49076; S 49076
Chemical Formula: C22H22N4O4S
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).IFNAR inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 values below 20 nmol/L. S49076 potently blocked cellular phosphorylation of MET, AXL, and FGFRs and inhibited downstream signaling in vitro and in vivo. In cell models, S49076 inPubMed ID:http://www.jbc.org/content/285/24/18838
