Product Name: Ruxolitinib phosphate
Chemical Name: (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile phosphate
SMILES Code: N#CC[C@@H](N1N=CC(C2=C3C(NC=C3)=NC=N2)=C1)C4CCCC4.O=P(O)(O)O
CAS NO: 69-78-3 Product: Bruceine A
Synonym: INCB018424 phosphate; INCB 018424 phosphate; INCB-018424 phosphate
Chemical Formula: C17H21N6O4P
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).PI3K/Akt/mTOR_Compound_Library inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Ruxolitinib (INCB018424) phosphate is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16557334
