Product Name: Rolapitant
Chemical Name: (5S,8S)-8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-1,9-diazaspiro[4.5]decan-2-one
SMILES Code: CC(C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)OCC2(CCC3(CCC(=O)N3)CN2)C4=CC=CC=C4
CAS NO: 18472-51-0 Product: TPT-260
Synonym: Varubi; SCH619734 SCH-619734; SCH 619734
Chemical Formula: C25H26F6N2O2
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).iGluR inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Rolapitant (Varubi) is a selective, bioavailable, CNS penetrant neurokinin NK1 receptor antagonist that shows behavioral effects in animals models of emesis.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16608916
