Product Name: RG3039
Chemical Name: 5-((1-(2,6-dichlorobenzyl)piperidin-4-yl)methoxy)quinazoline-2,4-diamine
SMILES Code: NC1=NC(N)=C2C(OCC3CCN(CC4=C(Cl)C=CC=C4Cl)CC3)=CC=CC2=N1.[H]Cl.[H]Cl
CAS NO: 369-07-3 Product: BBD
Synonym: RG 3039; RG-3039; PF06687859; PF 06687859; PF-06687859
Chemical Formula: C21H23Cl2N5O
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).FDA-approved_Drug_Library inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: RG3039 (PF-06687859) is a potent DcpS inhibitor. DcpS is a therapeutic target for spinal muscular atrophy. Spinal muscular atrophy (SMA) is caused by deletion or mutation of both copies of the SMN1 gene which produces an essential protein known as SMN. RGPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18027850
