Product Name: Pixantrone dimaleate
Chemical Name: 6,9-bis((2-aminoethyl)amino)benzo[g]isoquinoline-5,10-dione dimaleate
SMILES Code: O=C(C1=C(NCCN)C=CC(NCCN)=C12)C3=C(C=NC=C3)C2=O.O=C(O)/C=CC(O)=O.O=C(O)/C=CC(O)=O
CAS NO: 869288-64-2 Product: ETP-46321
Synonym: BBR2778 dimaleate; BBR 2778 dimaleate; BBR-2778 dimaleate
Chemical Formula: C25H27N5O10
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Casein Kinase inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Pixantrone (BBR2778 dimaleate) is a synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNAPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/9598866