Product Name: Palbociclib isethionate
Chemical Name: 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one 2-hydroxyethane-1-sulfonate
SMILES Code: O=C1C(C(C)=O)=C(C)C2=CN=C(NC3=NC=C(N4CCNCC4)C=C3)N=C2N1C5CCCC5.OCCS(=O)(O)=O
CAS NO: 28448-85-3 Product: Britannilactone
Synonym: PD0332991 isethionate; PD-0332991 isethionate; PD 0332991 isethionate
Chemical Formula: C26H35N7O6S
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Dopamine Receptor inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Palbociclib isethionate (PD-0332991 isethionate) is a highly specific inhibitor of Cdk4 (IC50=11 nM) and Cdk6 (IC50=16 nM), having no activity against a panel of 36 additional protein kinases. It selectively inhibits cyclin-dependent kinases (particularlyPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20209107
