Product Name: PS-48
Chemical Name: 5-(4-chlorophenyl)-3-phenyl-2Z-pentenoic acid
SMILES Code: ClC1=CC=C(CC/C(C2=CC=CC=C2)=C/C(O)=O)C=C1
CAS NO: 98079-51-7 Product: Amrubicin (hydrochloride)
Synonym: PS48
Chemical Formula: C17H15ClO2
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Salt-inducible Kinase SIK) inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: PS-48 is an allosteric phosphoinositide-dependent protein kinase-1 (PDK1) activator (Kd = 10.3 μM). Binds exclusively to the PIF-binding pocket of PDK1, distinct from the ATP binding site.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/9245214
