Product Name: PIM447
Chemical Name: N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide
SMILES Code: O=C(NC1=C([C@H]2C[C@@H](N)C[C@@H](C)C2)C=CN=C1)C3=NC(C4=C(F)C=CC=C4F)=C(F)C=C3
CAS NO: 113981-44-5 Product: CH5424802 (Hydrochloride)
Synonym: LGH447; PIM-447; LGH-447; PIM 447; LGH 447
Chemical Formula: C24H23F3N4O
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).ROS inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: PIM447 (LGH447) is a potent Moloney murine leukemia (PIM) 1, 2, and 3 kinase inhibitor. Pan proviral insertion site of Moloney murine leukemia (PIM) 1, 2, and 3 kinase inhibitors have recently begun to be tested in humans to assess whether pan PIM kinase PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/1741368
