Product Name: PI3K-IN-1
Chemical Name: N-[4-[[3-(3,5-dimethoxyanilino)quinoxalin-2-yl]sulfamoyl]phenyl]-3-methoxy-4-methylbenzamide
SMILES Code: CC1=C(C=C(C=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)NC3=NC4=CC=CC=C4N=C3NC5=CC(=CC(=C5)OC)OC)OC
CAS NO: 1420071-30-2 Product: Dobutamine (hydrochloride)
Synonym: XL765, SAR245409, Voxtalisib
Chemical Formula: C31H29N5O6S
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).PDK-1 inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: PI3K-IN-1 (XL765, SAR245409, Voxtalisib) is a dual inhibitor of both PI3K and mTOR, completely blocking phosphorylation of substrates at 8-16 µM. Similarly, XL765 is cytotoxic to glioblastoma multiforme (GBM) xenografts in vitro, with half maximal inhibitPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/9152599
