Product Name: PD-153035
Chemical Name: N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine
SMILES Code: COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC
CAS NO: 1337532-29-2 Product: B-Raf IN 1
Synonym: ZM 252868; AG 1517; Tyrphostin AG 1517; SU 5271; PD153035; PD-153035
Chemical Formula: C16H14BrN3O2
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).IRAK inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: PD153035 (ZM 252868, AG 1517) is a ATP-competitive EGFR inhibitor with an IC50 and Ki of 25 and 6 pM. PD153035 effectively blocks the enhancement of mitogenesis, induction of early gene expression, and oncogenic transformation that occur in response to EGPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17516547
