Product Name: PCI-24781
Chemical Name: 3-(dimethylaminomethyl)-N-[2-[4-(hydroxycarbamoyl)phenoxy]ethyl]-1-benzofuran-2-carboxamide
SMILES Code: O=C(C(O1)=C(CN(C)C)C2=C1C=CC=C2)NCCOC3=CC=C(C(NO)=O)C=C3
CAS NO: 113558-15-9 Product: Bay-K-8644 ((R)-(+)-)
Synonym: CRA 024781; CRA 24781; PCI 24781; Abexinostat
Chemical Formula: C21H23N3O5
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Monoamine Transporter inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: PCI-24781 (Abexinostat; CRA 24781) is a novel pan-HDAC inhibitor mostly targeting HDAC1 with Ki of 7 nM, modest potent to HDACs 2, 3, 6, and 10 and greater than 40-fold selectivity against HDAC8.PubMed ID:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895086/?tool=pmcentrez
