Product Name: Olcegepant
Chemical Name: N-((1R)-2-(((1S)-5-Amino-1-((4-(pyridin-4-yl)piperazin-1-yl)carbonyl)pentyl)amino)-1-(3,5-dibromo-4-hydroxybenzyl)-2-oxoethyl)-4-(2-oxo-1,4-dihydroquinazolin-3(2H)-yl)piperidine-1-carboxamide
SMILES Code: O=C(N1CCC(N2C(NC3=C(C=CC=C3)C2)=O)CC1)N[C@H](CC4=CC(Br)=C(O)C(Br)=C4)C(N[C@H](C(N5CCN(C6=CC=NC=C6)CC5)=O)CCCCN)=O
CAS NO: 936350-00-4 Product: Nepicastat (hydrochloride)
Synonym: BIBN-4096; BIBN-4096BS; BIBN4096BS; BIBN 4096BS
Chemical Formula: C38H47Br2N9O5
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Fatty Acid Synthase FAS) inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Olcegepant (BIBN-4096BS) is is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor, a key modulator in neurogenic inflammatory pain. In preclinical studies, olcegepant attenuated arterial dilatioPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22088482
