Product Name: Obeticholic Acid
Chemical Name: (4R)-4-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
SMILES Code: CCC1C2CC(CCC2(C3CCC4(C(C3C1O)CCC4C(C)CCC(=O)O)C)C)O
CAS NO: 18059-10-4 Product: AKBA
Synonym: INT747; 6-ECDCA
Chemical Formula: C26H44O4
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).GHSR inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Obeticholic Acid (INT747; 6-ECDCA) is a novel derivative of cholic acid which acts as a potent and selective FXR agonist displaying anticholeretic activity in an in vivo rat model of cholestasis. It inhibits vascular smooth muscle cell inflammation and miPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed?term=miR-122%20regulates%20p53%2FAkt%20signalling%20and%20the%20chemotherapy-induced%20apoptosis%20in%20cutaneous%20T-cell%20lymphoma.
