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Product Name: Necrostatin-1
Chemical Name: 5-(1H-indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone
SMILES Code: O=C(C(CC1=CNC2=C1C=CC=C2)N3)N(C)C3=S
CAS NO: 102625-70-7 Product: Satraplatin
Synonym: Necrostatin 1
Chemical Formula: C13H13N3OSMolecular Weight: 259.33
Appearance: Solid powderWeb Site:Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).PDHK inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM, which functions as an allosteric inhibitor of the death domain receptor-associated adaptor kinase RIP (RIP1) in the necroptosis pathway. While affectingPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17112576

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Author: DNA_ Alkylatingdna