Product Name: MLN4924
Chemical Name: ((1S,2S,4R)-4-(4-(((S)-2,3-dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate
SMILES Code: O=S(OC[C@H]1[C@@H](O)C[C@H](N2C=CC3=C(N[C@H]4CCC5=C4C=CC=C5)N=CN=C32)C1)(N)=O
CAS NO: 157843-41-9 Product: Veratramine
Synonym: Pevonedistat; TAK-924; TAK 924; TAK924; MLN-4924; MLN 4924
Chemical Formula: C21H25N5O4S
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Toxins_for_Antibody-drug_conjugates_research_Library inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: MLN4924 (Pevonedistat, TAK-924) is a small molecule inhibitor of Nedd8 activating enzyme (NAE) with potential antineoplastic activity. NAE inhibitor MLN4924 binds to and inhibits NAE, which may result in the inhibition of tumor cell proliferation and survPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19498465
