Product Name: ML216
Chemical Name: N-[4-fluoro-3-(trifluoromethyl)phenyl]-N’-[5-(4-pyridinyl)-1,3,4-thiadiazol-2-yl]-urea
SMILES Code: FC1=CC=C(NC(NC2=NN=C(C3=CC=NC=C3)S2)=O)C=C1C(F)(F)F
CAS NO: 132907-72-3 Product: Brinzolamide
Synonym: ML 216; ML-216; CID-49852229; CID49852229; CID 49852229
Chemical Formula: C15H9F4N5OS
Appearance: Light yellow solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Sodium Channel inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: ML216 is the first identified small molecule inhibitor of BLM helicase (IC50 = 1.8 μM) that is 28-fold selective against the related helicases RECQ1, RECQ5, and E. coli UvrD (IC50s ≥ 50 μM).PubMed ID:http://www.jimmunol.org/cgi/content/meeting_abstract/184/1_MeetingAbstracts/140.15
