Product Name: ML-277
Chemical Name: 2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide
SMILES Code: O=C(C1=CC=C2C(N=C(C3=CC=C(OC4=CC=C(Cl)C=C4)C=C3)N2)=C1)N
CAS NO: 865231-46-5 Product: TTNPB
Synonym: ML 277; ML277; Chk2 Inhibitor II
Chemical Formula: C20H14ClN3O2
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Oxytocin Receptor inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: ML-277 (Chk2 Inhibitor II) is a Chk2 (checkpoint kinase 2) inhibitor. BML-277 protects T cells from apoptosis by controlling the response of p53 to radiation-induced DNA breaks. ML-277 shows 1000-fold greater selectivity for the Chk2 serine/threonine kinaPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/12615581
