Product Name: M2698
Chemical Name: (S)-4-((2-(azetidin-1-yl)-1-(4-chloro-3-(trifluoromethyl)phenyl)ethyl)amino)quinazoline-8-carboxamide
SMILES Code: O=C(C1=CC=CC2=C(N[C@@H](C3=CC=C(Cl)C(C(F)(F)F)=C3)CN4CCC4)N=CN=C12)N
CAS NO: 900185-02-6 Product: Isavuconazole
Synonym: MSC2363318A
Chemical Formula: C21H19ClF3N5O
Appearance: Solid powderWeb Site:Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).c-Met_HGFR inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: M2698 (MSC2363318A) is an orally bioavailable, BBB penetrable p70S6K/Akt dual inhibitor, and is highly potent in vitro (IC50 1 nM for p70S6K, Akt1 and Akt3 inhibition; IC50 17 nM for pGSK3β indirect inhibition) and in vivo (IC50 15 nM for pS6 indirect inhPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/9544767