Product Name: LY2811376
Chemical Name: (S)-4-(2,4-difluoro-5-(pyrimidin-5-yl)phenyl)-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine
SMILES Code: NC1=N[C@](C)(C2=CC(C3=CN=CN=C3)=C(F)C=C2F)CCS1
CAS NO: 1457983-28-6 Product: Aldicarb (sulfone)
Synonym: LY 2811376; LY-2811376
Chemical Formula: C15H14F2N4S
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Topoisomerase inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: LY2811376 is a BACE1 inhibitor with marked Ab-lowering effects in animal models. LY2811376 treatment induces Aβ5-X peptides through alternative amyloid precursor protein cleavage. The β-secretase enzyme, β-site amyloid precursor protein-cleaving enzyme 1 PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/15269157
