Product Name: LY-333531 hydrochloride
Chemical Name: (12E,32E,7S)-7-((dimethylamino)methyl)-22,25-dihydro-11H,21H,31H-6-oxa-1,3(3,1)-diindola-2(3,4)-pyrrolacyclononaphane-22,25-dione hydrochloride
SMILES Code: O=C1NC(C2=C1C3=CN(C4=CC=CC=C34)CC[C@@H](CN(C)C)OCCN5C=C2C6=CC=CC=C56)=O.[H]Cl
CAS NO: 1453848-26-4 Product: Methoxy-PEPy
Synonym: Ruboxistaurin; LY333531; LY 333531
Chemical Formula: C28H29ClN4O3
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).p38 MAPK inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: LY-333531 (Ruboxistaurin) is a PKC beta inhibitor potentially for the treatment of diabetic nephropathy and diabetic macular edema. Ruboxistaurin attenuates diabetic nephropathy via modulation of TGF-β1/Smad and GRAP pathways.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18995898
