Product Name: LDN-214117
Chemical Name: 1-(4-(6-methyl-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)phenyl)piperazine
SMILES Code: COC1=C(OC)C(OC)=CC(C2=C(C)N=CC(C3=CC=C(N4CCNCC4)C=C3)=C2)=C1
CAS NO: 170105-16-5 Product: FGH10019
Synonym: LDN214117; LDN 214117
Chemical Formula: C25H29N3O3
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).MNK inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: LDN-214117 is a potent and selective ALK2 inhibitor with IC50 of 22 nM; > 100 fold selectivity for ALK5; also inhibits BMP6 (IC50=100 nM). There are currently no effective therapies for fibrodysplasia ossificans progressiva (FOP), a debilitating and prPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19509160
