Product Name: KM11060
Chemical Name: 7-chloro-4-(4-((4-chlorophenyl)sulfonyl)piperazin-1-yl)quinoline
SMILES Code: O=S(N1CCN(C2=CC=NC3=CC(Cl)=CC=C23)CC1)(C4=CC=C(Cl)C=C4)=O
CAS NO: 1708766 Product: Nonivamide
Synonym: KM-11060; KM 11060
Chemical Formula: C19H17Cl2N3O2S
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Inhibitor_Kit inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: KM11060 is a mutated F508del cystic fibrosis transmembrane conductance regulator (CFTR) corrector. The most common mutation (~90%) in the CFTR gene is a deletion of phenylalanine 508 (F508del). KM11060 is an analog of sildenafil, which restores a functionPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18271058