Product Name: Inauhzin
Chemical Name: 2-((5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio)-1-(10H-phenothiazin-10-yl)butan-1-one
SMILES Code: CCC(SC1=NN=C2C(NC3=C2C=CC=C3)=N1)C(N4C5=C(C=CC=C5)SC6=CC=CC=C46)=O
CAS NO: 1610537-15-9 Product: GDC-0834 (Racemate)
Synonym: INZ
Chemical Formula: C25H19N5OS2
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).CaMK inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Inauhzin (INZ) is a potent SIRT inhibitor, which effectively reactivates p53 by inhibiting SIRT1 activity, promotes p53-dependent apoptosis of human cancer cells without causing apparently genotoxic stress. Moreover, Inauhzin stabilizes p53 by increasing PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/11075290
