Product Name: INT-777
Chemical Name: (3α,5β,6α,7α,12α,23S)-6-ethyl-3,7,12-trihydroxy-cholane-23-carboxylic acid
SMILES Code: O[C@@H]1CC[C@@]2(C)[C@@]([C@@H](CC)[C@@H](O)[C@]3([H])[C@]2([H])C[C@H](O)[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)C[C@H](C)C(O)=O)([H])C1
CAS NO: 380607-77-2 Product: Zatebradine
Synonym: S-EMCA; INT777; INT 777
Chemical Formula: C27H46O5
Appearance: Solid powderWeb Site：Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Proton Pump inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: INT-777 (S-EMCA) is a novel potent and selective TGR5 agonist with remarkable in vivo activity (EC50=0.82 uM). It is active in vivo, stimulating the secretion of glucagon-like peptide-1 (GLP-1) in mice when given orally (30 mg/kg) after a glucose challengPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/7786288
