Product Name: HLCL-61
Chemical Name: 1-(9-ethyl-9H-carbazol-3-yl)-N-(2-methoxybenzyl)methanamine
SMILES Code: COC1=CC=CC=C1CNCC2=CC3=C(C=C2)N(CC)C4=C3C=CC=C4
CAS NO: 63699-78-5 Product: DHBS
Synonym: HLCL61; HLCL 61
Chemical Formula: C23H25ClN2O
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Neurological Disease inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: HLCL-61 is a potent and selective PRMT5 inhibitor for treatment of acute myeloid leukemia, which resulted in significantly increased expression of miR-29b and consequent suppression of Sp1 and FLT3 in AML cells. As a result, significant antileukemic activPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23138873