Product Name: GSK583
Chemical Name: 6‑(tert-Butylsulfonyl)‑N‑(5-fluoro‑1H‑indazol-3-yl)quinolin-4-amine
SMILES Code: FC1=CC2=C(NN=C2NC3=CC=NC4=CC=C(S(=O)(C(C)(C)C)=O)C=C34)C=C1
CAS NO: 73069-14-4 Product: β-Lapachone
Synonym: GSK 583; GSK-583
Chemical Formula: C20H19FN4O2S
Appearance: Solid powderWeb Site:Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).IRAK inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: GSK583 is a highly potent and selective inhibitor of RIP2 kinase with an IC50 of 5 nM. GSK583 has low clearance, moderate volumes of distribution, and moderate oral bioavailability in both rat and mouse.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/15380183?dopt=Abstract