Product Name: GSK484
Chemical Name: ((3S,4R)-3-amino-4-hydroxypiperidin-1-yl)(2-(1-(cyclopropylmethyl)-1H-indol-2-yl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-5-yl)methanone
SMILES Code: O[C@@H]1CCN(C[C@@H]1N)C(C2=CC3=C(C(OC)=C2)N(C)C(C4=CC5=C(N4CC6CC6)C=CC=C5)=N3)=O
CAS NO: 226954-04-7 Product: SB-3CT
Synonym: GSK-484; GSK 484
Chemical Formula: C27H31N5O3
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Inflammation/Immunology inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: GSK484 is a potent PAD-4 inhibitor (Protein-arginine deiminase type-4), which potently binds to the low-calcium form of PAD4 in a reversible manner (IC50 of 50 nM) and appears to be competitive with substrate. GSK484’s selectivity for PAD4 over PAD1-3 wasPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21546570
