Product Name: GSK2636771
Chemical Name: 2-methyl-1-(2-methyl-3-(trifluoromethyl)benzyl)-6-morpholino-1H-benzo[d]imidazole-4-carboxylic acid
SMILES Code: O=C(C1=C2C(N(CC3=CC=CC(C(F)(F)F)=C3C)C(C)=N2)=CC(N4CCOCC4)=C1)O
CAS NO: 54910-89-3 Product: Nitisinone
Synonym: GSK-2636771; GSK 2636771
Chemical Formula: C22H22F3N3O3
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).STAT inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: GSK2636771 is a potent, orally bioavailable and selective inhibitor of PI3Kβ (0.89 nM), with >900-fold selectivity over PI3Kα/PI3Kγ and >10-fold over PI3Kδ. It inhibits AKT phosphorylation and downstream signalling measured as decrease of PRAS40-, GPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/3125484
