Product Name: GSK2141795
Chemical Name: N-[(2S)-1-amino-3-(3,4-difluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-2-methylpyrazol-3-yl)furan-2-carboxamide
SMILES Code: CN1C(=C(C=N1)Cl)C2=C(OC(=C2)C(=O)NC(CC3=CC(=C(C=C3)F)F)CN)Cl
CAS NO: 3733-63-9 Product: ATN-161 (trifluoroacetate salt)
Synonym: Uprosertib; GSK 2141795; GSK-2141795
Chemical Formula: C18H16Cl2F2N4O2
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Flavonoids inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: GSK2141795 (Uprosertib) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GSK2141795 binds to and inhibits the activity of Akt, which may result in inhibPubMed ID:http://mct.aacrjournals.org/cgi/content/short/10/11_MeetingAbstracts/A94?rss=1
