Product Name: GNF-2
Chemical Name: 3-(6-((4-(trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)benzamide
SMILES Code: O=C(N)C1=CC=CC(C2=NC=NC(NC3=CC=C(OC(F)(F)F)C=C3)=C2)=C1
CAS NO: 1417329-24-8 Product: X-Gluc (Dicyclohexylamine)
Synonym: GNF 2; GNF2
Chemical Formula: C18H13F3N4O2
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Notch inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: GNF-2 is an allosteric inhibitor of Bcr-abl tyrosine kinase activity (IC50 = 267 nM); inhibits proliferation and induces apoptosis in Bcr-abl-expressing cells. Selective for Bcr-abl over a panel of serine, threonine and tyrosine kinases.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19284385
