Product Name: Fumitremorgin C
Chemical Name: 1,2,3,5aS,6,11,12S,14aS-octahydro-9-methoxy-12-(2-methyl-1-propen-1-yl)-5H,14H-pyrrolo[1”,2”:4′,5′]pyrazino[1′,2′:1,6]pyrido[3,4-b]indole-5,14-dione
SMILES Code: O=C(N1[C@@]2([H])CCC1)[C@]3([H])CC4=C(NC5=C4C=CC(OC)=C5)[C@@H](N3C2=O)/C=C(C)C
CAS NO: 938448-87-4 Product: TZ9
Synonym: Tryptoquivaline
Chemical Formula: C22H25N3O3
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Proteasome inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Fumitremorgin C (Tryptoquivaline) is a specific inhibitor of breast cancer resistance protein (BCRP/ABCG2) multidrug efflux transporter. At 5 μM, it significantly potentiates the toxicity of the chemotherapeutic drugs mitoxantrone, doxorubicin, and topotePubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16495249
