Product Name: Entrectinib
Chemical Name: N-[5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methylpiperazin-1-yl)-2-(oxan-4-ylamino)benzamide
SMILES Code: CN1CCN(CC1)C2=CC(=C(C=C2)C(=O)NC3=NNC4=C3C=C(C=C4)CC5=CC(=CC(=C5)F)F)NC6CCOCC6
CAS NO: 130964-39-5 Product: Lificiguat
Synonym: NMS-E628; RXDX-101
Chemical Formula: C31H34F2N6O2
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).RIP kinase inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Entrectinib (NMS-E628; RXDX-101) is an oral small molecule inhibitor of TrkA, TrkB and TrkC, as well as ROS1 and ALK, with high potency and selectivity. It has demonstrated potent pharmacological activity in preclinical studies.PubMed ID:http://abstracts.iovs.org/cgi/content/abstract/45/5/1204
