Product Name: EX-527
Chemical Name: 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
SMILES Code: O=C(C1C(NC2=C3C=C(Cl)C=C2)=C3CCC1)N
CAS NO: 1361030-48-9 Product: TBA-354
Synonym: EX527; Selisistat
Chemical Formula: C13H13ClN2O
Appearance: Solid powderWeb Site：Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Cathepsin inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Selisistat (EX-527) is a SirT1 inhibitor for treatment of Huntington’s disease. EX-527 inhibits Sirtuins by exploiting their unique NAD+-dependent deacetylation mechanism. Galectin-9 in Combination With EX-527 Prolongs the Survival of Cardiac AllogrPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed?term=15664519
