Product Name: E-52862
Chemical Name: 4-(2-((5-methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yl)oxy)ethyl)morpholine
SMILES Code: CC1=CC(OCCN2CCOCC2)=NN1C3=CC=C4C=CC=CC4=C3
CAS NO: 129580-63-8 Product: Palbociclib (isethionate)
Synonym: E 52862; E52862; S1RA
Chemical Formula: C20H23N3O2
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).gamma)-secretase inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: E-52862 (S1RA) is a selective sigma-1 receptor antagonist, with a reported binding affinity of Ki = 17.0 ± 7.0 nM, selective over the sigma-2 receptor and against a panel of other 170 receptors, enzymes, transporters and ion channels. In preclinical studiPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/9506869
