Product Name: Dapivirine
Chemical Name: 4-[[4-[(2,4,6-Trimethylphenyl)amino]-2-pyrimidinyl]amino]benzonitrile
SMILES Code: N#CC1=CC=C(NC2=NC=CC(NC3=C(C)C=C(C)C=C3C)=N2)C=C1
CAS NO: Product: MMAF (Hydrochloride)
Synonym: TMC120; TMC 120; TMC-120; R 147681; R-147681; R147681
Chemical Formula: C20H19N5
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).TAK1 inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Dapivirine (TMC120, R147681) is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM. The HIV-1 replication inhibitor dapivirine (DPV) is one of the most promising drug candidates being used in topical microbicide products for prevePubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/2353556
