Product Name: DASA-58
Chemical Name: 3-[[4-[(2,3-dihydro-1,4-benzodioxin-6-yl)sulfonyl]hexahydro-1H-1,4-diazepin-1-yl]sulfonyl]-benzenamine
SMILES Code: O=S(N1CCN(S(C2=CC=C(OCCO3)C3=C2)(=O)=O)CCC1)(C4=CC(N)=CC=C4)=O
CAS NO: 71203-35-5 Product: 5-GTP (trisodium salt)
Synonym: DASA58; DASA 58; ML-203; NCGC00185916
Chemical Formula: C19H23N3O6S2
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).CMV inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: DASA-58 is an selective activator of pyruvate kinase M2 (PKM2) with an AC90 value of 680 nM, and an AC50 value of 38 nM. DASA-58 converts PKM2 to a constitutively active enzyme state that is resistant to inhibition by tyrosine-phosphorylated proteins.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18408761
