Product Name: CYM-5442
Chemical Name: 2-((4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)amino)ethan-1-ol
SMILES Code: CCOC1=CC=C(C2=NC(C3=CC=CC4=C3CCC4NCCO)=NO2)C=C1OCC
CAS NO: 1364488-67-4 Product: Saxagliptin (hydrate)
Synonym: CYM 5442; CYM5442
Chemical Formula: C23H27N3O4
Appearance: Solid powderWeb Site：Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Protease-Activated Receptor PAR) inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: CYM-5442 is a highly-selective S1P1 (Spingosine 1-Phosphate Receptor 1) agonist. CYM-5442 reduces the severity of acute GVHD by inhibiting macrophage recruitment. CYM-5442 significantly inhibited but did not prevent aGVHD. CYM-5442 treatment downregulatedPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/7906660
