Product Name: CPI-360
Chemical Name: (R)-N-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(tetrahydro-2H-pyran-4-yl)ethyl)-1H-indole-3-carboxamide
SMILES Code: C[C@@H](N1C(C)=C(C(NCC2=C(C=C(NC2=O)C)OC)=O)C3=C1C=CC=C3)C4CCOCC4
CAS NO: 957135-43-2 Product: Exatecan
Synonym: CPI360; CPI 360
Chemical Formula: C25H31N3O4
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Eukaryotic Initiation Factor eIF) inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: CPI-360 is a potent, selective EZH2 inhibitor with IC50 of 0.5 nM and 2.5 nM nM for wt EZH2 and Y641N EZH2, respectively.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/12093318
