Product Name: Baricitinib phosphate
Chemical Name: 2-[1-ethylsulfonyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile;phosphoric acid
SMILES Code: CCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OP(=O)(O)O
CAS NO: 717824-30-1 Product: Helioxanthin derivative 5-4-2
Synonym: INCB 028050; LY 3009104; INCB028050; LY3009104; LY-3009104; INCB-028050
Chemical Formula: C16H20N7O6PS
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).NKCC inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Baricitinib (LY3009104, INCB028050) phosphate is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM in cell-free assays, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/7882331
