Product Name: BMS-911543
Chemical Name: N,N-dicyclopropyl-4-((1,5-dimethyl-1H-pyrazol-3-yl)amino)-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide
SMILES Code: O=C(C1=CC2=C(N(C)C=N3)C3=C(NC4=NN(C)C(C)=C4)N=C2N1CC)N(C5CC5)C6CC6
CAS NO: 546-43-0 Product: Zatebradine (hydrochloride)
Synonym: BMS911543; BMS 911543
Chemical Formula: C23H28N8O
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).GlyT inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: BMS-911543 is a potent and selective small-molecule inhibitor of JAK2, displays potent anti-proliferative and pharmacodynamic (PD) effects in cell lines dependent upon JAK2 signaling. This may lead to an induction of tumor cell apoptosis and a decrease inPubMed ID:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1782268/