Product Name: BMS-5
Chemical Name: N-[5-[1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]-2-thiazolyl]-2-methylpropanamide
SMILES Code: CC(C)C(NC1=NC=C(C2=CC(C(F)F)=NN2C3=C(Cl)C=CC=C3Cl)S1)=O
CAS NO: 60-70-8 Product: Ingenol Mebutate
Synonym: LIMKI-3; LIMKI 3; LIMKI3; BMS 5; BMS5
Chemical Formula: C17H14Cl2F2N4OS
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).HBV inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: BMS-5 (LIMKI-3) is a Potent LIM kinase inhibitor (IC50 values are 7 and 8 nM for LIMK1 and LIMK2 respectively). Inhibits cofilin phosphorylation in MDA-MB-231 breast cancer cells. Reduces MDA-MB-231 tumor cell invasion in a 3D matrigel invasion assay.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21144599
