Product Name: Avasimibe
Chemical Name: ((2,4,6-Tris(1-methylethyl)phenyl)acetyl)sulfamic acid 2,6-bis(1-methylethyl)phenyl ester
SMILES Code: CC(C)C1=C(OS(NC(CC2=C(C(C)C)C=C(C(C)C)C=C2C(C)C)=O)(=O)=O)C(C(C)C)=CC=C1
CAS NO: 18642-23-4 Product: 1-O-Acetylbritannilactone
Synonym: CI-1011; PD-148515; CI1011; PD148515; CI 1011; PD 148515
Chemical Formula: C29H43NO4S
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).CXCR inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Avasimibe (CI-1011; PD-148515) is a ACAT inhibitor incluing ACAT-1 and ACAT-2. Avasimibe can also reduce the synthesis and secretion of Apo B 100 in HepG2 cells. Avasimibe encapsulated in human serum albumin blocks cholesterol esterification for selectivePubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19789626
