Product Name: Afatinib dimaleate
Chemical Name: (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide dimaleate
SMILES Code: O=C(NC1=CC2=C(NC3=CC=C(F)C(Cl)=C3)N=CN=C2C=C1O[C@@H]4COCC4)/C=C/CN(C)C.O=C(O)/C=CC(O)=O.O=C(O)/C=CC(O)=O
CAS NO: 86764-11-6 Product: Telatinib
Synonym: BIBW 2992MA2; BIBW-2992; BIBW2992; BIBW 2992; Afatinib
Chemical Formula: C32H33ClFN5O11
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Prostaglandin Receptor inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Afatinib (BIBW-2992) dimaleate is an orally bioavailable dual receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. EGFR/HER2 tyrosine kinase inhibitor BIBW 2992 irreversibly binds to and inhibits human epidermal growth factor rPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20496265
