Product Name: AR-A014418
Chemical Name: N-(4-Methoxybenzyl)-N’-(5-nitro-1,3-thiazol-2-yl)urea
SMILES Code: COc1ccc(cc1)CNC(=O)Nc2ncc(s2)[N+](=O)[O-]
CAS NO: 1226895-20-0 Product: 5-FAM SE
Synonym: AR-AO 14418; AR 0133418; AR 014418; GSK 3β inhibitor
Chemical Formula: C12H12N4O4S
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Stem Cell_Wnt inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: AR-A014418 (SN 4521) is a labeled Glycogen Synthase Kinase 3β (GSK-3β) inhibitor. AR-A014418 suppresses pancreatic cancer cell growth via inhibition of GSK-3-mediated Notch1 expression. AR-A014418 decreases neuropathic pain in mice: evidence for the mechaPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20159992
