Product Name: APY29
Chemical Name: (E)-N-(6-((5-cyclopropyl-1H-pyrazol-3-yl)imino)-1,6-dihydropyrimidin-2-yl)-1H-benzo[d]imidazol-6-amine
SMILES Code: C12=CC(NC3=NC=C/C(N3)=NC4=NNC(C5CC5)=C4)=CC=C1N=CN2
CAS NO: 1502655-48-2 Product: Sagittatoside A
Synonym: APY 29; APY-29
Chemical Formula: C17H16N8
Appearance: Solid powderWeb Site：Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).DAPK inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: APY29 is an allosteric modulator of IRE1α which inhibits IRE1α autophosphorylation with IC50 of 280 nM and activates IRE1α RNase activity. ATP-competitive inhibitors of IRE1α promote dimerization and activation of RNase activity despite blocking kinase auPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21812414
